mutagen effect modification
- mutagen effect modification
Мутагенного эффекта модифицирование — изменение частоты и спектра мутаций, индуцируемых определенным мутагеном у данного объекта, вследствие перемены режима мутагенной обработки, а также использования веществ, модифицирующих эффект мутагена, причем степень модифицирования зависит от времени действия модификатора (до, во время или после мутагенного воздействия). Мутаген-модифицирующие факторы разделяются на увеличивающие (сенсибилизаторы) и уменьшающие (протекторы) частоту мутаций и повреждающий эффект мутагенной обработки. Некоторые отдельные факторы и специальные режимы обработки мутагеном, снижая частоту хромосомных аберраций и повреждающий эффект его действия, могут одновременно удерживать и даже повышать уровень мутирования или репродукции, тем самым повышая выход мутаций в расчете на число выживших особей (см. Антимутагены. Кислородный эффект. Мутагенный эффект).
Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО.
Арефьев В.А., Лисовенко Л.А., науч. ред. Л.И.Патрушев.
1995.
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